اخبار داغ سرطان

T-47D

T-47D از کارسینوم مجاری پستان از یک خانم 54 ساله جدا شده اند. این رده سلول دارای مورفولوژی اپتلیوم است و دارای رسپتورهای استروئیدی مثل استروژن و پروژسترون است.  T-47D فاقد رسپتور فاکتور رشد اپیدرمال نوع 2 (her2) هستند و پروتئین سرکوبگر تومور p53 را بصورت جهش یافته دارد.

T47d 2

T47d 1

TNC also induces EMT-like change in T-47D cells. Breast cancer cell line T-47D showed EMT-like change by TNC and TGF-β1/TNC treatments for 5 to 6 days. The EMT was exhibited at the margin of cell cluster, to a lesser extent than for MCF-7 cells (left). Immunofluorescence exhibited reduced β-catenin staining of intercellular contacts in the cells moving outside the cluster (right). Scale bars = 50 μmTNC also induces EMT-like change in T-47D cells. Breast cancer cell line T-47D showed EMT-like change by TNC and TGF-β1/TNC treatments for 5 to 6 days. The EMT was exhibited at the margin of cell cluster, to a lesser extent than for MCF-7 cells. Immunofluorescence exhibited reduced β-catenin staining of intercellular contacts in the cells moving outside the cluster (right). Scale bars = 50 μm
Acknowledgement: These pictures were published by National Infrastructure of Cell Line Resource and Keiki Nagaharu. For any further information kindly refere to this article

0/5 : Not rated

مشاوره مستقیم با ما

لینک به این مرکز

لینک به این مرکز

آمار وب سایت